Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells-Reference-Cited by-同舟云学术

Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells

Published:2017-07-26 Issue:7666 Volume:548 Page:219-223
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Choi Jiho,Huebner Aaron J.,Clement Kendell,Walsh Ryan M.,Savol Andrej,Lin Kaixuan,Gu Hongcang,Di Stefano Bruno,Brumbaugh Justin,Kim Sang-Yong,Sharif Jafar,Rose Christopher M.,Mohammad Arman,Odajima Junko,Charron Jean,Shioda Toshi,Gnirke Andreas,Gygi Steven,Koseki Haruhiko,Sadreyev Ruslan I.,Xiao Andrew,Meissner Alexander,Hochedlinger Konrad

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature23274.pdf

Reference49 articles.

1. Ying, Q.-L. et al. The ground state of embryonic stem cell self-renewal. Nature 453, 519–523 (2008)

2. Raggioli, A., Junghans, D., Rudloff, S. & Kemler, R. β-catenin is vital for the integrity of mouse embryonic stem cells. PLoS One 9, e86691 (2014)

3. Chen, H. et al. Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells. Proc. Natl Acad. Sci. USA 112, E5936–E5943 (2015)

4. Chen, R. Z., Pettersson, U., Beard, C., Jackson-Grusby, L. & Jaenisch, R. DNA hypomethylation leads to elevated mutation rates. Nature 395, 89–93 (1998)

5. Gaudet, F. et al. Induction of tumors in mice by genomic hypomethylation. Science 300, 489–492 (2003)

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