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A dose-escalating phase I of imatinib mesylate with fixed dose of metronomic cyclophosphamide in targeted olid tumours

  • Published:2013-10-22 Issue:10 Volume:109 Page:2574-2578
  • ISSN:0007-0920
  • Container-title:British Journal of Cancer
  • language:en
  • Short-container-title:Br J Cancer

Author:

Adenis A,Ray-Coquard I,Italiano A,Chauzit E,Bui-Nguyen B,Blay J-Y,Tresch-Bruneel E,Fournier C,Clisant S,Amela E Y,Cassier P A,Molimard M,Penel N

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference22 articles.

1. Awada A, Dirix L, Manso Sanchez L, Xu B, Luu T, Diéras V, Hershman DL, Agrapart V, Ananthakrishnan R, Staroslawska E (2013) Safety and efficacy of neratinib (HKI-272) plus vinorelbine in the treatment of patients with ErbB2-positive metastatic breast cancer pretreated with anti-HER2 therapy. Ann Oncol 24: 109–116.

2. Blay JY, Le Cesne A, Ray-Coquard I, Bui BN, Duffaud F, Delbaldo C, Adenis A, Viens P, Rios M, Bompas E, Cupissol D, Guillemet C, Kerbrat P, Fayette J, Chabaud S, Berthaud P, Perol D (2007) Prospective multicentric randomized phase III study of imatinib in patients with advanced gastrointestinal stromal tumors comparing interruption versus continuation of treatment beyond 1 year: the French Sarcoma Group. J Clin Oncol 25: 1107–1113.

3. Bouchet S, Chauzit E, Ducint D, Castaing N, Canal-Raffin M, Moore N, Titier K, Molimard M (2011) Simultaneous determination of nine tyrosine kinase inhibitors by 96-well solid-phase extraction and ultra performance LC/MS-MS. Clin Chim Acta 412: 1060–1067.

4. Bousquet G, Alexandre J, Le Tourneau C, Goldwasser F, Faivre S, de Mont-Serrat H, Kaiser R, Misset JL, Raymond E (2011) Phase I study of BIBF 1120 with docetaxel and prednisolone in metastatic chemo-naive hormone-refractory prostate cancer patients. Br J Cancer 105: 1640–1645.

5. De Jonge MJ, Dumez H, Kitzen JJ, Beuselinck B, Verweij J, Courtney R, Battista A, Brega N, Schöffski P (2011) Phase I safety and pharmacokinetic study of SU-014813 in combination with docetaxel in patients with advanced solid tumours. Eur J Cancer 47: 1328–1335.

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