Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion-Reference-Cited by-同舟云学术

Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion

Published:2012-04-13 Issue:11 Volume:31 Page:2498-2510
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:

Author:

Ganuza Miguel¹,Sáiz-Ladera Cristina²,Cañamero Marta³,Gómez Gonzalo⁴,Schneider Ralph⁵,Blasco María A⁵,Pisano David⁴,Paramio Jesús M²,Santamaría David¹,Barbacid Mariano¹

Affiliation:

1. Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO); Madrid Spain

2. Department of Basic Research, Molecular Oncology Unit, CIEMAT; Madrid Spain

3. Comparative Pathology Unit, Biotechnology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO); Madrid Spain

4. Bioinformatics Unit, Structural Biology and Biocomputing Programme, Centro Nacional de Investigaciones Oncológicas (CNIO); Madrid Spain

5. Telomeres and Telomerase Group, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO); Madrid Spain

Publisher

Wiley

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Reference37 articles.

1. Cdk2 knockout mice are viable;Berthet;Curr Biol,2003

2. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche;Blanpain;Cell,2004

3. E2F target genes: unraveling the biology;Bracken;Trends Biochem Sci,2004

4. High-throughput telomere length quantification by FISH and its application to human population studies;Canela;Proc Natl Acad Sci USA,2009

5. Aging;Chuttani;Handbook of Physiology,1995

Cited by 95 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7);European Journal of Medicinal Chemistry;2024-10

2. Activation of the CDK7 Gene, Coding for the Catalytic Subunit of the Cyclin-Dependent Kinase (CDK)-Activating Kinase (CAK) and General Transcription Factor II H, by the Trans-Activator Protein Tax of Human T-Cell Leukemia Virus Type-1;Genes;2024-08-15

3. Age-Associated Calcification: Insights from Murine Models;Gout, Urate, and Crystal Deposition Disease;2024-08-06

4. Super-enhancer omics in stem cell;Molecular Cancer;2024-08-01

5. Genome-wide functional CRISPR screen reveals CDK7 as a targetable therapeutic vulnerability for head and neck cancer;2024-07-29