Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial-Reference-Cited by-同舟云学术

Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial

Published:2010-04 Issue:4 Volume:18 Page:666-668
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Brentjens Renier,Yeh Raymond,Bernal Yvette,Riviere Isabelle,Sadelain Michel

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference6 articles.

1. Targeting tumours with genetically enhanced T lymphocytes;Sadelain;Nat Rev Cancer,2003

2. Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15;Brentjens;Nat Med,2003

3. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor;Maher;Nat Biotechnol,2002

4. Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts;Brentjens;Clin Cancer Res,2007

5. The promise and potential pitfalls of chimeric antigen receptors;Sadelain;Curr Opin Immunol,2009

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