Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice-Reference-Cited by-同舟云学术

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Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

Published:2011-02 Issue:2 Volume:19 Page:345-354
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Malerba Alberto,Sharp Paul S,Graham Ian R,Arechavala-Gomeza Virginia,Foster Keith,Muntoni Francesco,Wells Dominic J,Dickson George

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference39 articles.

1. Very mild muscular dystrophy associated with the deletion of 46% of dystrophin;England;Nature,1990

2. An explanation for the phenotypic differences between patients bearing partial deletions of the DMD locus;Monaco;Genomics,1988

3. X chromosome-linked muscular dystrophy (mdx) in the mouse;Bulfield;Proc Natl Acad Sci USA,1984

4. Somatic reversion/suppression of the mouse mdx phenotype in vivo;Hoffman;J Neurol Sci,1990

5. Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology;Alter;Nat Med,2006

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