Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease-Reference-Cited by-同舟云学术

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Published:2016-05-04 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Bell Catherine C.,Hendriks Delilah F. G.,Moro Sabrina M. L.,Ellis Ewa,Walsh Joanne,Renblom Anna,Fredriksson Puigvert Lisa,Dankers Anita C. A.,Jacobs Frank,Snoeys Jan,Sison-Young Rowena L.,Jenkins Rosalind E.,Nordling Åsa,Mkrtchian Souren,Park B. Kevin,Kitteringham Neil R.,Goldring Christopher E. P.,Lauschke Volker M.,Ingelman-Sundberg Magnus

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep25187.pdf

Reference45 articles.

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2. Hewitt, N. J. et al. Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance and Hepatotoxicity Studies. Drug Metab. Rev. 39, 159–234, 10.1080/03602530601093489 (2015).

3. Rowe, C. et al. Proteome-wide analyses of human hepatocytes during differentiation and dedifferentiation. Hepatology 58, 799–809, 10.1002/hep.26414 (2013).

4. Elaut, G. et al. Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures. Curr. Drug Metab. 7, 629–660 (2006).

5. Lin, R.-Z., Chou, L.-F., Chien, C.-C. M. & Chang, H.-Y. Dynamic analysis of hepatoma spheroid formation: roles of E-cadherin and β1-integrin. Cell Tissue Res. 324, 411–422, 10.1007/s00441-005-0148-2 (2006).

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