Protein kinase C, an elusive therapeutic target?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd3871.pdf
Reference258 articles.
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2. Geraldes, P. & King, G. L. Activation of protein kinase C isoforms and its impact on diabetic complications. Circ. Res. 106, 1319–1331 (2010).
3. Toton, E., Ignatowicz, E., Skrzeczkowska, K. & Rybczynska, M. Protein kinase Cɛ as a cancer marker and target for anticancer therapy. Pharmacol. Rep. 63, 19–29 (2011).
4. Inagaki, K., Churchill, E. & Mochly-Rosen, D. Epsilon protein kinase C as a potential therapeutic target for the ischemic heart. Cardiovasc. Res. 70, 222–230 (2006).
5. Ferreira, J. C., Brum, P. C. & Mochly-Rosen, D. βIIPKC and ɛPKC isozymes as potential pharmacological targets in cardiac hypertrophy and heart failure. J. Mol. Cell. Cardiol. 51, 479–484 (2011).
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