The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation

Author:

He Jun,Gao Hao-xue,Yang Na,Zhu Xiao-dong,Sun Run-bin,Xie Yuan,Zeng Cai-hong,Zhang Jing-wei,Wang Jian-kun,Ding Fei,Aa Ji-ye,Wang Guang-ji

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference67 articles.

1. Oates PJ. Aldose reductase inhibitors and diabetic kidney disease. Curr Opin Investig Drugs. 2010;11:402–17.

2. Nishikawa T, Edelstein D, Brownlee M. The missing link: a single unifying mechanism for diabetic complications. Kidney Int Suppl. 2000;77:S26–30.

3. Hers HG. Le mécanisme de la transformation de glucose en fructose par les vésicules séminales. Biochim Biophys Acta. 1956;22:202–3.

4. Dunlop M. Aldose reductase and the role of the polyol pathway in diabetic nephropathy. Kidney Int Suppl. 2000;77:S3–12.

5. Yabe-Nishimura C. Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications. Pharmacol Rev. 1998;50:21–34.

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