DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
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Published:2015-10-05
Issue:11
Volume:47
Page:1316-1325
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Kretzmer Helene, , Bernhart Stephan H, Wang Wei, Haake Andrea, Weniger Marc A, Bergmann Anke K, Betts Matthew J, Carrillo-de-Santa-Pau Enrique, Doose Gero, Gutwein Jana, Richter Julia, Hovestadt Volker, Huang Bingding, Rico Daniel, Jühling Frank, Kolarova Julia, Lu Qianhao, Otto Christian, Wagener Rabea, Arnolds Judith, Burkhardt Birgit, Claviez Alexander, Drexler Hans G, Eberth Sonja, Eils Roland, Flicek Paul, Haas Siegfried, Hummel Michael, Karsch Dennis, Kerstens Hinrik H D, Klapper Wolfram, Kreuz Markus, Lawerenz Chris, Lenze Dido, Loeffler Markus, López Cristina, MacLeod Roderick A F, Martens Joost H A, Kulis Marta, Martín-Subero José Ignacio, Möller Peter, Nagel Inga, Picelli Simone, Vater Inga, Rohde MariusORCID, Rosenstiel Philip, Rosolowski Maciej, Russell Robert BORCID, Schilhabel Markus, Schlesner Matthias, Stadler Peter FORCID, Szczepanowski Monika, Trümper Lorenz, Stunnenberg Hendrik G, Küppers Ralf, Ammerpohl Ole, Lichter Peter, Siebert Reiner, Hoffmann Steve, Radlwimmer BernhardORCID,
Publisher
Springer Science and Business Media LLC
Reference55 articles.
1. Lai, A.Y. et al. DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation. Genome Res. 23, 2030–2041 (2013). 2. Lee, S.T. et al. A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network. Nucleic Acids Res. 40, 11339–11351 (2012). 3. Shaknovich, R. et al. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. Blood 118, 3559–3569 (2011). 4. Basso, K. & Dalla-Favera, R. Germinal centres and B cell lymphomagenesis. Nat. Rev. Immunol. 15, 172–184 (2015). 5. Lenz, G. & Staudt, L.M. Aggressive lymphomas. N. Engl. J. Med. 362, 1417–1429 (2010).
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