Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer’s disease neuropathological deficits-Reference-Cited by-同舟云学术

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Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer’s disease neuropathological deficits

Published:2016-03-22 Issue:3 Volume:22 Page:407-416
ISSN:1359-4184
Container-title:Molecular Psychiatry
language:en
Short-container-title:Mol Psychiatry

Author:

Shah S A,Yoon G H,Chung S S,Abid M N,Kim T H,Lee H Y,Kim M O

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Molecular Biology

Link

http://www.nature.com/articles/mp201623.pdf

Reference34 articles.

1. Cutler RG, Kelly J, Storie K, Pedersen WA, Tammara A, Hatanpaa K et al. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer’s disease. Proc Natl Acad Sci USA 2004; 101: 2070–2075.

2. Bandaru VVR, Troncoso J, Wheeler D, Pletnikova O, Wang J, Conant K et al. ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer’s but not normal brain. Neurobiol Aging 2009; 30: 591–599.

3. Xiong H, Callaghan D, Jones A, Walker DG, Lue LF, Beach TG et al. Cholesterol retention in Alzheimer’s brain is responsible for high beta- and gamma-secretase activities and Abeta production. Neurobiol Dis 2008; 29: 422–437.

4. Panchal AM, Loeper J, Cossec JC, Perruchini C, Lazar A, Pompon D et al. Enrichment of cholesterol in microdissected Alzheimer’s disease senile plaques as assessed by mass spectrometry. J Lipid Res 2010; 51: 598–605.

5. Fernandez A, Llacuna L, Fernandez-Checa JC, Colell A . Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity. J Neurosci 2009; 29: 6394–6405.

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