Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility

Author:

Dieterich Klaus,Soto Rifo Ricardo,Faure Anne Karen,Hennebicq Sylviane,Ben Amar Baha,Zahi Mohamed,Perrin Julia,Martinez Delphine,Sèle Bernard,Jouk Pierre-Simon,Ohlmann Théophile,Rousseaux Sophie,Lunardi Joel,Ray Pierre F

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Reference26 articles.

1. Pryor, J.L. et al. Microdeletions in the Y chromosome of infertile men. N. Engl. J. Med. 336, 534–539 (1997).

2. Nistal, M., Paniagua, R. & Herruzo, A. Multi-tailed spermatozoa in a case with asthenospermia and teratospermia. Virchows Arch. B Cell Pathol. 26, 111–118 (1977).

3. Escalier, D. Human spermatozoa with large heads and multiple flagella: a quantitative ultrastructural study of 6 cases. Biol. Cell 48, 65–74 (1983).

4. Escalier, D. Genetic approach to male meiotic division deficiency: the human macronuclear spermatozoa. Mol. Hum. Reprod. 8, 1–7 (2002).

5. German, J., Rasch, E.M., Huang, C.Y., MacLeod, J. & Imperato-McGinley, J. Human infertility due to production of multiple-tailed spermatozoa with excessive amounts of DNA. Am. J. Hum. Genet. 33, 64A (1981).

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