DNA repair deficiency and neurological disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
http://www.nature.com/articles/nrn2559.pdf
Reference201 articles.
1. Bender, A. et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nature Genet. 38, 515–517 (2006).
2. Katyal, S. & McKinnon, P. J. DNA strand breaks, neurodegeneration and aging in the brain. Mech. Ageing Dev. 129, 483–491 (2008).
3. Kraytsberg, Y. et al. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nature Genet. 38, 518–520 (2006).
4. Nouspikel, T. & Hanawalt, P. C. When parsimony backfires: neglecting DNA repair may doom neurons in Alzheimer's disease. Bioessays 25, 168–173 (2003).
5. Chan, W. Y., Lorke, D. E., Tiu, S. C. & Yew, D. T. Proliferation and apoptosis in the developing human neocortex. Anat. Rec. 267, 261–276 (2002).
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