Identification of type 2 diabetes loci in 433,540 East Asian individuals
Author:
Spracklen Cassandra N.ORCID, Horikoshi Momoko, Kim Young JinORCID, Lin Kuang, Bragg FionaORCID, Moon Sanghoon, Suzuki Ken, Tam Claudia H. T.ORCID, Tabara Yasuharu, Kwak Soo-Heon, Takeuchi FumihikoORCID, Long Jirong, Lim Victor J. Y., Chai Jin-FangORCID, Chen Chien-Hsiun, Nakatochi MasahiroORCID, Yao Jie, Choi Hyeok Sun, Iyengar Apoorva K., Perrin Hannah J., Brotman Sarah M.ORCID, van de Bunt Martijn, Gloyn Anna L.ORCID, Below Jennifer E., Boehnke MichaelORCID, Bowden Donald W., Chambers John C., Mahajan AnubhaORCID, McCarthy Mark I.ORCID, Ng Maggie C. Y.ORCID, Petty Lauren E., Zhang Weihua, Morris Andrew P., Adair Linda S., Akiyama Masato, Bian Zheng, Chan Juliana C. N., Chang Li-Ching, Chee Miao-Li, Chen Yii-Der Ida, Chen Yuan-Tsong, Chen ZhengmingORCID, Chuang Lee-Ming, Du Shufa, Gordon-Larsen Penny, Gross Myron, Guo Xiuqing, Guo Yu, Han SoheeORCID, Howard Annie-Green, Huang Wei, Hung Yi-Jen, Hwang Mi Yeong, Hwu Chii-Min, Ichihara Sahoko, Isono Masato, Jang Hye-Mi, Jiang Guozhi, Jonas Jost B.ORCID, Kamatani YoichiroORCID, Katsuya Tomohiro, Kawaguchi Takahisa, Khor Chiea-ChuenORCID, Kohara Katsuhiko, Lee Myung-ShikORCID, Lee Nanette R., Li Liming, Liu JianjunORCID, Luk Andrea O., Lv Jun, Okada YukinoriORCID, Pereira Mark A., Sabanayagam CharumathiORCID, Shi Jinxiu, Shin Dong Mun, So Wing Yee, Takahashi AtsushiORCID, Tomlinson BrianORCID, Tsai Fuu-JenORCID, van Dam Rob M., Xiang Yong-Bing, Yamamoto KenORCID, Yamauchi ToshimasaORCID, Yoon Kyungheon, Yu Canqing, Yuan Jian-MinORCID, Zhang LiangORCID, Zheng WeiORCID, Igase MichiyaORCID, Cho Yoon Shin, Rotter Jerome I.ORCID, Wang Ya-XingORCID, Sheu Wayne H. H., Yokota Mitsuhiro, Wu Jer-Yuarn, Cheng Ching-YuORCID, Wong Tien-Yin, Shu Xiao-Ou, Kato Norihiro, Park Kyong-SooORCID, Tai E-Shyong, Matsuda Fumihiko, Koh Woon-Puay, Ma Ronald C. W.ORCID, Maeda Shiro, Millwood Iona Y., Lee Juyoung, Kadowaki TakashiORCID, Walters Robin G.ORCID, Kim Bong-Jo, Mohlke Karen L.ORCID, Sim XuelingORCID
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Reference83 articles.
1. Mahajan, A. et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat. Genet. 50, 1505–1513 (2018). 2. Suzuki, K. et al. Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. Nat. Genet. 51, 379–386 (2019). 3. Moon, Y. S. et al. Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity. Mol. Cell. Biol. 22, 5585–5592 (2002). 4. van de Bunt, M. et al. The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis. PLoS One 8, e55272 (2013). 5. Scott, L. J. et al. The genetic regulatory signature of type 2 diabetes in human skeletal muscle. Nat. Commun. 7, 11764 (2016).
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