A genomic mutational constraint map using variation in 76,156 human genomes
Author:
Chen Siwei, Francioli Laurent C., Goodrich Julia K., Collins Ryan L., Kanai MasahiroORCID, Wang QingboORCID, Alföldi JessicaORCID, Watts Nicholas A., Vittal Christopher, Gauthier Laura D., Poterba Timothy, Wilson Michael W., Tarasova Yekaterina, Phu WilliamORCID, Grant Riley, Yohannes Mary T., Koenig Zan, Farjoun YossiORCID, Banks Eric, Donnelly Stacey, Gabriel Stacey, Gupta Namrata, Ferriera Steven, Tolonen Charlotte, Novod Sam, Bergelson Louis, Roazen David, Ruano-Rubio Valentin, Covarrubias Miguel, Llanwarne Christopher, Petrillo Nikelle, Wade Gordon, Jeandet Thibault, Munshi Ruchi, Tibbetts Kathleen, Abreu Maria, Aguilar Salinas Carlos A., Ahmad Tariq, Albert Christine M., Ardissino Diego, Armean Irina M., Atkinson Elizabeth G., Atzmon Gil, Barnard John, Baxter Samantha M., Beaugerie Laurent, Benjamin Emelia J., Benjamin David, Boehnke Michael, Bonnycastle Lori L., Bottinger Erwin P., Bowden Donald W., Bown Matthew J., Brand Harrison, Brant Steven, Brookings Ted, Bryant Sam, Calvo Sarah E., Campos Hannia, Chambers John C., Chan Juliana C., Chao Katherine R., Chapman Sinéad, Chasman Daniel I., Chisholm Rex, Cho Judy, Chowdhury Rajiv, Chung Mina K., Chung Wendy K., Cibulskis Kristian, Cohen Bruce, Connolly Kristen M., Correa Adolfo, Cummings Beryl B., Dabelea Dana, Danesh John, Darbar Dawood, Darnowsky Phil, Denny Joshua, Duggirala Ravindranath, Dupuis Josée, Ellinor Patrick T., Elosua Roberto, Emery James, England Eleina, Erdmann Jeanette, Esko Tõnu, Evangelista Emily, Fatkin Diane, Florez Jose, Franke Andre, Fu Jack, Färkkilä Martti, Garimella Kiran, Gentry Jeff, Getz Gad, Glahn David C., Glaser Benjamin, Glatt Stephen J., Goldstein David, Gonzalez Clicerio, Groop Leif, Gudmundsson Sanna, Haessly Andrea, Haiman Christopher, Hall Ira, Hanis Craig L., Harms Matthew, Hiltunen Mikko, Holi Matti M., Hultman Christina M., Jalas Chaim, Kallela Mikko, Kaplan Diane, Kaprio Jaakko, Kathiresan Sekar, Kenny Eimear E., Kim Bong-Jo, Kim Young Jin, King Daniel, Kirov George, Kooner Jaspal, Koskinen Seppo, Krumholz Harlan M., Kugathasan Subra, Kwak Soo Heon, Laakso Markku, Lake Nicole, Langsford Trevyn, Laricchia Kristen M., Lehtimäki Terho, Lek Monkol, Lipscomb Emily, Loos Ruth J. F., Lu Wenhan, Lubitz Steven A., Luna Teresa Tusie, Ma Ronald C. W., Marcus Gregory M., Marrugat Jaume, Mattila Kari M., McCarroll Steven, McCarthy Mark I., McCauley Jacob L., McGovern Dermot, McPherson Ruth, Meigs James B., Melander Olle, Metspalu Andres, Meyers Deborah, Minikel Eric V., Mitchell Braxton D., Mootha Vamsi K., Naheed Aliya, Nazarian Saman, Nilsson Peter M., O’Donovan Michael C., Okada Yukinori, Ongur Dost, Orozco Lorena, Owen Michael J., Palmer Colin, Palmer Nicholette D., Palotie Aarno, Park Kyong Soo, Pato Carlos, Pulver Ann E., Rader Dan, Rahman Nazneen, Reiner Alex, Remes Anne M., Rhodes Dan, Rich Stephen, Rioux John D., Ripatti Samuli, Roden Dan M., Rotter Jerome I., Sahakian Nareh, Saleheen Danish, Salomaa Veikko, Saltzman Andrea, Samani Nilesh J., Samocha Kaitlin E., Sanchis-Juan Alba, Scharf Jeremiah, Schleicher Molly, Schunkert Heribert, Schönherr Sebastian, Seaby Eleanor G., Shah Svati H., Shand Megan, Sharpe Ted, Shoemaker Moore B., Shyong Tai, Silverman Edwin K., Singer-Berk Moriel, Sklar Pamela, Smith Jonathan T., Smith J. Gustav, Soininen Hilkka, Sokol Harry, Son Rachel G., Soto Jose, Spector Tim, Stevens Christine, Stitziel Nathan O., Sullivan Patrick F., Suvisaari Jaana, Tai E. Shyong, Taylor Kent D., Teo Yik Ying, Tsuang Ming, Tuomi Tiinamaija, Turner Dan, Tusie-Luna Teresa, Vartiainen Erkki, Vawter Marquis, Wang Lily, Wang Arcturus, Ware James S., Watkins Hugh, Weersma Rinse K., Weisburd Ben, Wessman Maija, Whiffin Nicola, Wilson James G., Xavier Ramnik J., O’Donnell-Luria AnneORCID, Solomonson Matthew, Seed Cotton, Martin Alicia R.ORCID, Talkowski Michael E., Rehm Heidi L.ORCID, Daly Mark J.ORCID, Tiao Grace, Neale Benjamin M.ORCID, MacArthur Daniel G., Karczewski Konrad J.ORCID,
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Reference86 articles.
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