Reduced reproductive success is associated with selective constraint on human genes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-022-04549-9.pdf
Reference75 articles.
1. Lek, M. et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature 536, 285–291 (2016).
2. Cassa, C. A. et al. Estimating the selective effects of heterozygous protein-truncating variants from human exome data. Nat. Genet. 49, 806–810 (2017).
3. Collins, R. L. et al. A structural variation reference for medical and population genetics. Nature 581, 444–451 (2020).
4. Weghorn, D. et al. Applicability of the mutation-selection balance model to population genetics of heterozygous protein-truncating variants in humans. Mol. Biol. Evol. 36, 1701–1710 (2019).
5. Darwin, C. The Descent of Man, and Selection in Relation to Sex (A. L. Burt, 1874); https://doi-org.ezp.lib.cam.ac.uk/10.5962/bhl.title.16749
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