TMPRSS2 is a functional receptor for human coronavirus HKU1-Reference-Cited by-同舟云学术

TMPRSS2 is a functional receptor for human coronavirus HKU1

Published:2023-10-25 Issue:7990 Volume:624 Page:207-214
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Saunders Nell^ORCID,Fernandez Ignacio,Planchais Cyril^ORCID,Michel Vincent^ORCID,Rajah Maaran Michael,Baquero Salazar Eduard,Postal Jeanne,Porrot Francoise^ORCID,Guivel-Benhassine Florence,Blanc Catherine^ORCID,Chauveau-Le Friec Gaëlle,Martin Augustin,Grzelak Ludivine,Oktavia Rischa Maya,Meola Annalisa,Ahouzi Olivia,Hoover-Watson Hunter,Prot Matthieu,Delaune Deborah^ORCID,Cornelissen Marion,Deijs Martin,Meriaux Véronique,Mouquet Hugo,Simon-Lorière Etienne^ORCID,van der Hoek Lia^ORCID,Lafaye Pierre^ORCID,Rey Felix^ORCID,Buchrieser Julian^ORCID,Schwartz Olivier^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-023-06761-7.pdf

Reference70 articles.

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2. Bertram, S. et al. TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is wxpressed in viral target cells in the respiratory epithelium. J. Virol. 87, 6150–6160 (2013).

3. Glowacka, I. et al. Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response. J. Virol. 85, 4122–4134 (2011).

4. Shirato, K., Kawase, M. & Matsuyama, S. Wild-type human coronaviruses prefer cell-surface TMPRSS2 to endosomal cathepsins for cell entry. Virology 517, 9–15 (2018).

5. Shirato, K., Kawase, M. & Matsuyama, S. Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2. J. Virol. 87, 12552–12561 (2013).

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