GABAA receptor signalling mechanisms revealed by structural pharmacology

Author:

Masiulis Simonas,Desai Rooma,Uchański Tomasz,Serna Martin Itziar,Laverty Duncan,Karia Dimple,Malinauskas Tomas,Zivanov Jasenko,Pardon Els,Kotecha Abhay,Steyaert Jan,Miller Keith W.,Aricescu A. Radu

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference69 articles.

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2. Barnard, E. A. et al. International Union of Pharmacology. XV. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 50, 291–313 (1998).

3. Sigel, E. & Steinmann, M. E. Structure, function, and modulation of GABAA receptors. J. Biol. Chem. 287, 40224–40231 (2012).

4. Möhler, H. GABAA receptors in central nervous system disease: anxiety, epilepsy, and insomnia. J. Recept. Signal Transduct. 26, 731–740 (2006).

5. Olsen, R. W. Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands. Neurochem. Res. 39, 1924–1941 (2014).

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