Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders
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Published:2023-03-22
Issue:3
Volume:1
Page:210-223
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ISSN:2731-6076
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Container-title:Nature Mental Health
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language:en
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Short-container-title:Nat. Mental Health
Author:
Hatoum Alexander S.ORCID, Colbert Sarah M. C.ORCID, Johnson Emma C.ORCID, Huggett Spencer B., Deak Joseph D.ORCID, Pathak Gita A., Jennings Mariela V., Paul Sarah E.ORCID, Karcher Nicole R.ORCID, Hansen Isabella, Baranger David A. A.ORCID, Edwards AlexisORCID, Grotzinger Andrew D.ORCID, Adkins Daniel E., Adkins Amy E., Alanne-Kinnunen Mervi, Alexander Jeffry C., Aliev Fazil, Bacanu Silviu-Alin, Batzler Anthony, Biernacka Joanna M., Bierut Laura J., Bigdeli Tim B., Blagonravova Anna, Boardman Jason D., Boden Joseph M., Boomsma Dorret I., Brown Sandra A., Bucholz Kathleen K., Chen Danfeng, Chen Li-Shiun, Choi Doo-Sup, Chou S. Patricia, Cichon Sven, Copeland William E., Corley Robin P., Degenhardt Franziska, Di Forti Marta, Diazgranados Nancy, Dick Danielle M., Domingue Benjamin W., Eriksson Johan G., Farrer Lindsay A., Foo Jerome C., Foroud Tatiana M., Fox Louis, Frank Josef, Frye Mark A., Gaebel Wolfgang, Gainetdinov Raul R., Giegling Ina, Gillespie Nathan A., Goate Alison M., Goldman David, Gordon Scott, Hack Laura M., Hancock Dana B., Harris Kathleen Mullan, Hartmann Annette M., Heath Andrew C., Heilmann-Heimbach Stefanie, Herms Stefan, Hesselbrock Victor, Hewitt John K., Hickie Ian, Hodgkinson Colin, Hoffmann Per, Hopfer Christian, Horwood John, Hottenga Jouke Jan, Howrigan Daniel Patrick, Iacono William G., Ising Marcus, Johnson Eric O., Kaprio Jaakko, Karpyak Victor M., Kendler Kenneth S., Kennedy Martin A., Keyes Margaret, Kibitov Alexander, Kiefer Falk, Konte Bettina, Kramer John, Krauter Kenneth, Krupitsky Evgeny M., Kuperman Samuel, Lahti Jari, Lahti-Pulkkinen Marius, Lai Dongbing, Levchenko Anastasia, Ligthart Lannie, Lind Penelope A., Lucae Susanne, Lynskey Michael T., Madden Pamela A. F., Maes Hermine H., Magnusson Patrik K. E., Maher Brion S., Mann Karl, Männistö Satu, Martin Nicholas G., Mbarek Hamdi, McGue Matt, McQueen Matthew B., Medland Sarah E., Meyers Jacquelyn L., Montgomery Grant W., Müller-Myhsok Bertram, Neale Benjamin M., Nelson Elliot C., Nöthen Markus M., Nurnberger John I., Palotie Aarno, Palviainen Teemu, Pearson John F., Pedersen Nancy L., Penninx Brenda W. J. H., Peterson Roseann E., Porjesz Bernice, Preuss Ulrich W., Quattrone Diego, Räikkönen Katri, Reynolds Maureen D., Rice John P., Ridinger Monika, Rietschel Marcella, Riley Brien P., Ripatti Samuli, Rose Richard J., Rujescu Dan, Rybakova Ksenia V., Ryu Euijung, Saccone Nancy L., Salvatore Jessica E., Scherbaum Norbert, Schuckit Marc A., Schwandt Melanie, Shen Pei-Hong, Sherva Richard, Silberg Judy, Stallings Michael C., Stein Dan J., Streit Fabian, Strohmaier Jana, Tarter Ralph E., Thomas Nathaniel, Vanyukov Michael M., Vrieze Scott, Wall Tamara L., Walters Raymond K., Webb Bradley T., Wedow Robbee, Wendt Frank, Wetherill Leah, Whitfield John B., Witt Stephanie, Wodarz Norbert, Wright Margaret J., Hartz Sarah M., Zellers Stephanie, Zhang Haitao, Zhao Hongyu, Zhou Hang, Zill Peter, Zillich Lea, Tucker-Drob Elliot M.ORCID, Kranzler Henry R.ORCID, Davis Lea K.ORCID, Sanchez-Roige SandraORCID, Polimanti RenatoORCID, Gelernter JoelORCID, Edenberg Howard J., Bogdan Ryan, Agrawal ArpanaORCID,
Funder
U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Publisher
Springer Science and Business Media LLC
Reference76 articles.
1. Degenhardt, L. et al. The impact of cohort substance use upon likelihood of transitioning through stages of alcohol and cannabis use and use disorder: findings from the Australian National Survey on Mental Health and Wellbeing. Drug Alcohol Rev. 37, 546–556 (2018). 2. Peacock, A. et al. Global statistics on alcohol, tobacco and illicit drug use: 2017 status report. Addiction 113, 1905–1926 (2018). 3. Reitsma, M. B. et al. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and initiation among young people in 204 countries and territories, 1990–2019. Lancet Public Health 6, e472–e481 (2021). 4. Odds of dying. Injury Facts https://injuryfacts.nsc.org/all-injuries/preventable-death-overview/odds-of-dying/ (accessed 3 December 2021). 5. Vanyukov, M. M. An eternal epidemic: 1. Why substance use problems persist. Preprint at PsyArXiv https://psyarxiv.com/tkm5u/ (2021).
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