The role of FLT3 in haematopoietic malignancies

Author:

Stirewalt Derek L.,Radich Jerald P.

Publisher

Springer Science and Business Media LLC

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference127 articles.

1. Matthews, W., Jordan, C. T., Wiegand, G. W., Pardoll, D. & Lemischka, I. R. A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell 65, 1143–1152 (1991).

2. Rosnet, O., Marchetto, S., deLapeyriere, O. & Birnbaum, D. Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family. Oncogene 6, 1641–1650 (1991). References 1 and 2 describe the initial cloning and expression of the mouse Fms-like tyrosine kinase 3 ( Flt3 ) gene.

3. Rosnet, O. et al. Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. Blood 82, 1110–1119 (1993).

4. Small, D. et al. STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells. Proc. Natl Acad. Sci. USA 91, 459–463 (1994). References 3 and 4 describe the initial cloning and expression of the human FLT3 gene.

5. Rosnet, O. et al. Close physical linkage of the FLT1 and FLT3 genes on chromosome 13 in man and chromosome 5 in mouse. Oncogene 8, 173–179 (1993).

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