The role of orexin in motivated behaviours
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
http://www.nature.com/articles/nrn3837.pdf
Reference148 articles.
1. Sakurai, T. & Mieda, M. Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal. Trends Pharmacol. Sci. 32, 451–462 (2011).
2. Etori, K., Saito, Y. C., Tsujino, N. & Sakurai, T. Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice. Front. Neurosci. 8, 8 (2014).
3. Harris, G. C., Wimmer, M. & Aston-Jones, G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature 437, 556–559 (2005). This work demonstrated, for the first time, roles for orexin neurons and VTA orexin receptors in reward-based learning and memory.
4. Haynes, A. C. et al. A selective orexin-1 receptor antagonist reduces food consumption in male and female rats. Regul. Pept. 96, 45–51 (2000).
5. Aston-Jones, G. et al. Lateral hypothalamic orexin/hypocretin neurons: a role in reward-seeking and addiction. Brain Res. 1314, 74–90 (2010).
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