Principles and challenges of genome-wide DNA methylation analysis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg2732.pdf
Reference174 articles.
1. Zhang, X. et al. Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis. Cell 126, 1189–1201 (2006). This study provided the first comprehensive DNA methylation analysis of a eukaryotic genome using whole-genome tiling arrays on affinity-enriched DNA.
2. Zilberman, D., Gehring, M., Tran, R. K., Ballinger, T. & Henikoff, S. Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nature Genet. 39, 61–69 (2007).
3. Zhang, X., Shiu, S., Cal, A. & Borevitz, J. O. Global analysis of genetic, epigenetic and transcriptional polymorphisms in Arabidopsis thaliana using whole genome tiling arrays. PLoS Genet. 4, e1000032 (2008).
4. Jones, P. A. The DNA methylation paradox. Trends Genet. 15, 34–37 (1999).
5. Hellman, A. & Chess, A. Gene body-specific methylation on the active X chromosome. Science 315, 1141–1143 (2007).
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