Sumoylation of Flotillin-1 promotes EMT in metastatic prostate cancer by suppressing Snail degradation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/s41388-018-0641-1.pdf
Reference44 articles.
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2. Santamaría A, Castellanos E, Gómez V, Benedit P, Renau-Piqueras J, Morote J, et al. PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts. Mol Cell Biol. 2005;25:1900–11.
3. Jang D, Kwon H, Jeong K, Lee J, Pak Y. Essential role of flotillin-1 palmitoylation in the intracellular localization and signaling function of IGF-1 receptor. J Cell Sci. 2015;128:2179–90.
4. Amaddii M, Meister M, Banning A, Tomasovic A, Mooz J, Rajalingam K, et al. Flotillin-1/reggie-2 protein plays dual role in activation of receptor-tyrosine kinase/mitogen-activated protein kinase signaling. J Biol Chem. 2012;287:7265–78.
5. Meister M, Bänfer S, Gärtner U, Koskimies J, Amaddii M, Jacob R, et al. Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo. Oncogenesis. 2017;6:e344.
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