Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies-Reference-Cited by-同舟云学术

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

Published:2020-09-28 Issue:12 Volume:27 Page:1125-1133
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Linse Sara^ORCID,Scheidt Tom^ORCID,Bernfur Katja,Vendruscolo Michele^ORCID,Dobson Christopher M.^ORCID,Cohen Samuel I. A.,Sileikis Eimantas^ORCID,Lundqvist Martin,Qian Fang,O’Malley Tiernan^ORCID,Bussiere Thierry^ORCID,Weinreb Paul H.^ORCID,Xu Catherine K.,Meisl Georg^ORCID,Devenish Sean R. A.,Knowles Tuomas P. J.^ORCID,Hansson Oskar^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

https://www.nature.com/articles/s41594-020-0505-6.pdf

Reference52 articles.

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3. Härd, T. & Lendel, C. Inhibition of amyloid formation. J. Mol. Biol. 421, 441–465 (2012).

4. Walsh, D. M. et al. Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416, 535–539 (2002).

5. Cohen, S. I. A. et al. A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers. Nat. Struct. Mol. Biol. 22, 207–213 (2015).

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