SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

Author:

Wrobel Antoni G.ORCID,Benton Donald J.ORCID,Xu Pengqi,Roustan Chloë,Martin Stephen R.,Rosenthal Peter B.ORCID,Skehel John J.,Gamblin Steven J.ORCID

Funder

Cancer Research UK

Wellcome Trust

RCUK | Medical Research Council

Sun Yat-sen University

100 Top Talents Program of Sun Yat-sen University & the Sanming Project of Medicine in Shenzhen

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Reference35 articles.

1. Masters, P. S. & Perlman S. in Fields Virology 6th edn, Vol. 1 (eds Howley, P. M. & Knipe, D. M.) 825–858 (Lippincott Williams & Wilkins, 2013).

2. Zhou, P. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579, 270–273 (2020).

3. Wu, F. et al. A new coronavirus associated with human respiratory disease in China. Nature 579, 265–269 (2020).

4. Li, W. et al. Bats are natural reservoirs of SARS-like coronaviruses. Science 310, 676–679 (2005).

5. Yang, L. et al. Novel SARS-like betacoronaviruses in bats, China, 2011. Emerg. Infect. Dis. 19, 989–991 (2013).

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