The microbiota in adaptive immune homeostasis and disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature18848.pdf
Reference135 articles.
1. Ivanov, I. I. et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139, 485–498 (2009). Together with ref. 50, this study shows that a subset of the microbiota specifically affects the accumulation of T H 17 cells in the intestine.
2. Wu, H.-J. et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 32, 815–827 (2010).
3. Sivan, A. et al. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science 350, 1084–1089 (2015). Together with refs 125 and 126, this study shows that a subset of the microbiota can have an effect on the efficacy of cancer therapy.
4. Atarashi, K. et al. Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 500, 232–236 (2013). This study and ref. 5 show that a rationally selected consortium of bacteria can specifically induce T reg cells in the intestine that function in systemic immune regulation.
5. Atarashi, K. et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 331, 337–341 (2011).
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