p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep38067.pdf
Reference43 articles.
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3. Meek, D. W. Tumour suppression by p53: a role for the DNA damage response? Nature reviews. Cancer 9, 714–723, doi: 10.1038/nrc2716 (2009).
4. Donehower, L. A. et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356, 215–221, doi: 10.1038/356215a0 (1992).
5. Ciriello, G. et al. Emerging landscape of oncogenic signatures across human cancers. Nature genetics 45, 1127–1133, doi: 10.1038/ng.2762 (2013).
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