Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/7700831.pdf
Reference36 articles.
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3. Wang S, Ghosh RN, Chellappan SP . Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation. Mol Cell Biol. 1998;18:7487–7498.
4. Lau QC, Achenbach TV, Borchers O, Muller R, Slater EP . In vivo pro-apoptotic and antitumor efficacy of a c-Raf antisense phosphorothioate oligonucleotide: relationship to tumor size. Antisense Nucleic Acid Drug Dev. 2002;12:11–20.
5. Liu X, Yan S, Zhou T, Terada Y, Erikson RL . The MAP kinase pathway is required for entry into mitosis and cell survival. Oncogene. 2004;23:763–776.
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