Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg.2016.13.pdf
Reference274 articles.
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2. Versteege, I. et al. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394, 203–206 (1998).
3. Lee, R. S. et al. A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J. Clin. Invest. 122, 2983–2988 (2012).
4. Mack, S. C. et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature 506, 445–450 (2014). This paper reported an absence of recurrent mutations in a subtype of paediatric posterior fossa ependymoma, suggesting the existence of alternative, non-mutational mechanisms for cancer initiation.
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