Prophylactic versus Preemptive modified donor lymphocyte infusion for high-risk acute leukemia after allogeneic hematopoietic stem cell transplantation: a multicenter retrospective study

Author:

Yang Luxin,Lai Xiaoyu,Yang Ting,Lu Ying,Liu Lizhen,Shi Jimin,Zhao Yanmin,Wu YiboORCID,Chen Yi,Yu Jian,Xiao HaowenORCID,Ouyang Guifang,Ren Jinhua,Cao Junjie,Hu YongxianORCID,Tan Yamin,Ye Yishan,Cai Zhen,Xu Weiqun,Huang HeORCID,Luo YiORCID

Publisher

Springer Science and Business Media LLC

Subject

Transplantation,Hematology

Reference39 articles.

1. Horowitz M, Schreiber H, Elder A, Heidenreich O, Vormoor J, Toffalori C, et al. Epidemiology and biology of relapse after stem cell transplantation. Bone Marrow Transpl. 2018;53:1379–89. https://doi.org/10.1038/s41409-018-0171-z.

2. Lazaryan A, Dolan M, Zhang M-J, Wang H-L, Kharfan-Dabaja MA, Marks DI et al. Impact of cytogenetic abnormalities on outcomes of adult Philadelphia- negative acute lymphoblastic leukemia after allogeneic hematopoietic s tem cell transplantation: a study by the Acute Leukemia Working Commit tee of the Center for International Blood and Marrow Transplant Resear ch. Haematologica; 105: 1329-38 https://doi.org/10.3324/haematol.2019.220756.

3. Yan CH, Liu DH, Liu KY, Xu LP, Liu YR, Chen H, et al. Risk stratification-directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation. Blood. 2012;119:3256–62. https://doi.org/10.1182/blood-2011-09-380386.

4. Dholaria B, Savani BN, Labopin M, Luznik L, Ruggeri A, Mielke S, et al. Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the Acute Leukemia Working Party of the EBMT. Haematologica. 2020;105:47–58. https://doi.org/10.3324/haematol.2019.219790.

5. Yuan XL, Tan YM, Shi JM, Zhao YM, Yu J, Lai XY, et al. Preemptive low-dose interleukin-2 or DLI for late-onset minimal residual disease in acute leukemia or myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation. Ann Hematol. 2021;100:517–27. https://doi.org/10.1007/s00277-020-04326-6.

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