WWP2 is an E3 ubiquitin ligase for PTEN

Author:

Maddika Subbareddy,Kavela Sridhar,Rani Neelam,Palicharla Vivek Reddy,Pokorny Jenny L.,Sarkaria Jann N.,Chen Junjie

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Reference40 articles.

1. Carnero, A., Blanco-Aparicio, C., Renner, O., Link, W. & Leal, J. F. The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Current Cancer Drug Targets 8, 187–198 (2008).

2. Li, J. et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943–1947 (1997).

3. Steck, P.A. et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15, 356–362 (1997).

4. Guldberg, P. et al. Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res. 57, 3660–3663 (1997).

5. Rhei, E. et al. Mutation analysis of the putative tumour suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res. 57, 3657–3659 (1997).

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