Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2017277.pdf
Reference50 articles.
1. Feng H, Shuda M, Chang Y, Moore PS . Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science 2008; 319: 1096–1100.
2. Houben R, Shuda M, Weinkam R, Schrama D, Feng H, Chang Y et al. Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens. J Virol 2010; 84: 7064–7072.
3. Busam KJ, Jungbluth AA, Rekthman N, Coit D, Pulitzer M, Bini J et al. Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas. Am J Surg Pathol 2009; 33: 1378–1385.
4. Rodig SJ, Cheng J, Wardzala J, DoRosario A, Scanlon JJ, Laga AC et al. Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus. J Clin Invest 2012; 122: 4645–4653.
5. Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS et al. T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc Natl Acad Sci USA 2008; 105: 16272–16277.
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