Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice-Reference-Cited by-同舟云学术

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

Published:2019-07-02 Issue:1 Volume:10 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Dash Prasanta K.,Kaminski Rafal,Bella Ramona,Su Hang,Mathews Saumi,Ahooyi Taha M.,Chen Chen,Mancuso Pietro,Sariyer Rahsan,Ferrante Pasquale,Donadoni Martina,Robinson Jake A.,Sillman Brady,Lin Zhiyi,Hilaire James R.,Banoub Mary,Elango Monalisha,Gautam Nagsen,Mosley R. Lee,Poluektova Larisa Y.,McMillan JoEllyn,Bade Aditya N.,Gorantla Santhi,Sariyer Ilker K.,Burdo Tricia H.,Young Won-Bin,Amini Shohreh,Gordon Jennifer,Jacobson Jeffrey M.,Edagwa Benson,Khalili Kamel,Gendelman Howard E.

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/s41467-019-10366-y.pdf

Reference68 articles.

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3. Deeks, S. G. et al. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nat. Med. 22, 839–850 (2016).

4. Hutter, G. et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. New Engl. J. Med. 360, 692–698 (2009).

5. Gupta, R. K. et al. HIV-1 remission following CCR5Delta32/Delta32 haematopoietic stem-cell transplantation. Nature 568, 244–248 (2019).

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