Tumor-derived RHOA mutants interact with effectors in the GDP-bound state-Reference-Cited by-同舟云学术

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Tumor-derived RHOA mutants interact with effectors in the GDP-bound state

Published:2024-08-21 Issue:1 Volume:15 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Lin Yuan^ORCID,Ramelot Theresa A.^ORCID,Senyuz Simge^ORCID,Gursoy Attila^ORCID,Jang Hyunbum^ORCID,Nussinov Ruth^ORCID,Keskin Ozlem,Zheng Yi^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

CancerFree KIDS Foundation

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41467-024-51445-z.pdf

Reference68 articles.

1. Etienne-Manneville, S. & Hall, A. Rho GTPases in cell biology. Nature 420, 629–635 (2002).

2. Hodge, R. G. & Ridley, A. J. Regulating Rho GTPases and their regulators. Nat. Rev. Mol. cell Biol. 17, 496–510 (2016).

3. Haga, R. B. & Ridley, A. J. Rho GTPases: Regulation and roles in cancer cell biology. Small GTPases 7, 207–221 (2016).

4. Vetter, I. R. & Wittinghofer, A. The guanine nucleotide-binding switch in three dimensions. Science 294, 1299–1304 (2001).

5. Cherfils, J. & Zeghouf, M. Regulation of small GTPases by GEFs, GAPs, and GDIs. Physiol. Rev. 93, 269–309 (2013).

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