The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-017-02339-w.pdf
Reference49 articles.
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3. Medeiros, A. A. Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics. Clin. Infect. Dis. 24, S19–S45 (1997). Suppl 1.
4. Ambler, R. P. The structure of beta-lactamases. Philos. Trans. R. Soc. B 289, 321–331 (1980).
5. Wang, Z., Fast, W., Valentine, A. M. & Benkovic, S. J. Metallo-beta-lactamase: structure and mechanism. Curr. Opin. Chem. Biol. 3, 614–622 (1999).
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