Abstract
AbstractStringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.
Funder
The National Social Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference18 articles.
1. WHO. Coronavirus disease 2019 (COVID-19) Situation Report—51. Data as reported by national authorities by 10 AM CET 11 March 2020 (WHO, 2020).
2. Prevention measures taken at Sanmin residential community in Wuhan—Xinhua | English.news.cn http://www.xinhuanet.com/english/2020-05/11/c_139048342.htm (2020).
3. Gandhi, M., Yokoe, D. S. & Havlir, D. V. Asymptomatic transmission, the Achilles’ heel of current strategies to control Covid-19. N. Engl. J. Med. 382, 2158–2160 (2020).
4. He, D. et al. The relative transmissibility of asymptomatic COVID-19 infections among close contacts. Int. J. Infect. Dis. 94, 145–147 (2020).
5. Arons, M. M. et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N. Engl. J. Med. 382, 2081–2090 (2020).
Cited by
136 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献