Abstract
AbstractEndogenous attention is the cognitive function that selects the relevant pieces of sensory information to achieve goals and it is known to be controlled by dorsal fronto-parietal brain areas. Here we expand this notion by identifying a control attention area located in the temporal lobe. By combining a demanding behavioral paradigm with functional neuroimaging and diffusion tractography, we show that like fronto-parietal attentional areas, the human posterior inferotemporal cortex exhibits significant attentional modulatory activity. This area is functionally distinct from surrounding cortical areas, and is directly connected to parietal and frontal attentional regions. These results show that attentional control spans three cortical lobes and overarches large distances through fiber pathways that run orthogonally to the dominant anterior-posterior axes of sensory processing, thus suggesting a different organizing principle for cognitive control.
Funder
Leon Levy Foundation
Microsoft Research
National Science Foundation
U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering
Microsoft
Google Cloud Platform, and the Indiana University Areas of Emergent Research “Learning: Brains, Machines, and Children,” the Indiana University Pervasive Technology Institute
New York Stem Cell Foundation
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
The New York Stem Cell Foundation; W.A.F. is a New York Stem Cell Foundation – Robertson Investigator;
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference117 articles.
1. Goldstein, B., Chun, M. M. & Wolfe, J. M. “Visual attention” in Blackwell Handbook of Perception, (ed. Goldstein, B. E.) pp. 272–310 (Blackwell Publishers Ltd., Oxford, UK, 2001).
2. Heilman, K. M. & Valenstein E. Frontal lobe neglect in man. Neurology 22, 660–664 (1972).
3. Heilman, K. M., Watson, R. T., Bower, D. & Valenstein, E. Right hemisphere dominance for attention. Rev. Neurol. 139, 15–17 (1983).
4. Vallar, G. & Perani, D. The anatomy of unilateral neglect after right-hemisphere stroke lesions. A clinical/CT-scan correlation study in man. Neuropsychologia 24, 609–622 (1986).
5. Mort, D. J. et al. The anatomy of visual neglect. Brain 126, 1986–1997 (2003).
Cited by
29 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献