Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya
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Published:2021-06-25
Issue:1
Volume:12
Page:
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ISSN:2041-1723
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Container-title:Nature Communications
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language:en
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Short-container-title:Nat Commun
Author:
Adetifa Ifedayo M. O.ORCID, Uyoga SophieORCID, Gitonga John N., Mugo Daisy, Otiende Mark, Nyagwange James, Karanja Henry K., Tuju James, Wanjiku Perpetual, Aman Rashid, Mwangangi Mercy, Amoth Patrick, Kasera Kadondi, Ng’ang’a Wangari, Rombo Charles, Yegon Christine, Kithi Khamisi, Odhiambo Elizabeth, Rotich Thomas, Orgut Irene, Kihara Sammy, Bottomley ChristianORCID, Kagucia Eunice W.ORCID, Gallagher Katherine E.ORCID, Etyang Anthony, Voller Shirine, Lambe TeresaORCID, Wright DanielORCID, Barasa Edwine, Tsofa Benjamin, Bejon Philip, Ochola-Oyier Lynette I., Agweyu Ambrose, Scott J. Anthony G.ORCID, Warimwe George M.ORCID
Abstract
AbstractObserved SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Reference28 articles.
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