Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson’s disease pathogenesis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/s41467-019-08858-y.pdf
Reference81 articles.
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3. Sulzer, D. & Surmeier, D. J. Neuronal vulnerability, pathogenesis, and Parkinson’s disease. Mov. Disord. 28, 715–724 (2013).
4. Bensaid, M., Michel, P. P., Clark, S. D., Hirsch, E. C. & Francois, C. Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson’s disease. Exp. Neurol. 275(Pt 1), 209–219 (2016).
5. Szego, E. M., Gerhardt, E., Outeiro, T. F. & Kermer, P. Dopamine-depletion and increased alpha-synuclein load induce degeneration of cortical cholinergic fibers in mice. J. Neurol. Sci. 310, 90–95 (2011).
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