Forecasting influenza activity using machine-learned mobility map

Author:

Venkatramanan Srinivasan,Sadilek AdamORCID,Fadikar Arindam,Barrett Christopher L.ORCID,Biggerstaff Matthew,Chen Jiangzhuo,Dotiwalla Xerxes,Eastham Paul,Gipson Bryant,Higdon Dave,Kucuktunc Onur,Lieber Allison,Lewis Bryan L.ORCID,Reynolds Zane,Vullikanti Anil K.,Wang Lijing,Marathe Madhav

Abstract

AbstractHuman mobility is a primary driver of infectious disease spread. However, existing data is limited in availability, coverage, granularity, and timeliness. Data-driven forecasts of disease dynamics are crucial for decision-making by health officials and private citizens alike. In this work, we focus on a machine-learned anonymized mobility map (hereon referred to as AMM) aggregated over hundreds of millions of smartphones and evaluate its utility in forecasting epidemics. We factor AMM into a metapopulation model to retrospectively forecast influenza in the USA and Australia. We show that the AMM model performs on-par with those based on commuter surveys, which are sparsely available and expensive. We also compare it with gravity and radiation based models of mobility, and find that the radiation model’s performance is quite similar to AMM and commuter flows. Additionally, we demonstrate our model’s ability to predict disease spread even across state boundaries. Our work contributes towards developing timely infectious disease forecasting at a global scale using human mobility datasets expanding their applications in the area of infectious disease epidemiology.

Funder

United States Department of Defense | Defense Threat Reduction Agency

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

National Science Foundation

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

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