Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients-Reference-Cited by-同舟云学术

Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients

Published:2021-05-24 Issue:6 Volume:2 Page:629-642
ISSN:2662-1347
Container-title:Nature Cancer
language:en
Short-container-title:Nat Cancer

Author:

Biasco Luca,Izotova Natalia,Rivat Christine,Ghorashian Sara^ORCID,Richardson Rachel,Guvenel Aleks,Hough Rachael,Wynn Robert,Popova Bilyana,Lopes Andre,Pule Martin,Thrasher Adrian J.,Amrolia Persis J.^ORCID

Funder

Wellcome Trust

DH | National Institute for Health Research

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Link

http://www.nature.com/articles/s43018-021-00207-7.pdf

Reference23 articles.

1. Sallusto, F., Lenig, D., Förster, R., Lipp, M. & Lanzavecchia, A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature https://doi.org/10.1038/35005534 (1999).

2. Gattinoni, L. et al. A human memory T cell subset with stem cell-like properties. Nat. Med. 17, 1290–1297 (2011).

3. Heslop, H. E. et al. Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients. Blood https://doi.org/10.1182/blood-2009-08-239186 (2010).

4. Berger, C. et al. Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates. J. Clin. Invest. https://doi.org/10.1172/JCI32103 (2008).

5. Biasco, L. et al. In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells. Sci. Transl. Med. 7, 273ra13 (2015).

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