Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28-Reference-Cited by-同舟云学术

Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28

Published:1997-07 Issue:7 Volume:4 Page:527-531
ISSN:1072-8368
Container-title:Nature Structural Biology
language:
Short-container-title:Nat Struct Mol Biol

Author:

Metzler William J.,Bajorath Jürgen,Fenderson William,Shaw Shyh-Yu,Constantine Keith L.,Naemura Joseph,Leytze Gina,Peach Robert J.,Lavoie Thomas B.,Mueller Luciano,Linsley Peter S.

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Biochemistry,Structural Biology

Reference27 articles.

1. The B7 and CD28 receptor families

2. CTLA-4 can function as a negative regulator of T cell activation

3. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.

4. Enhancement of Antitumor Immunity by CTLA-4 Blockade

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