Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome-Reference-Cited by-同舟云学术

Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome

Published:2017-06-19 Issue:8 Volume:49 Page:1267-1273
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Logan Grant J,Dane Allison P,Hallwirth Claus V,Smyth Christine M,Wilkie Emilie E,Amaya Anais K,Zhu Erhua,Khandekar Neeta,Ginn Samantha L,Liao Sophia H Y,Cunningham Sharon C,Sasaki Natsuki,Cabanes-Creus Martí,Tam Patrick P L,Russell David W,Lisowski Leszek,Alexander Ian E

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng.3893.pdf

Reference58 articles.

1. Mingozzi, F. & High, K.A. Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges. Nat. Rev. Genet. 12, 341–355 (2011).

2. Gaj, T., Epstein, B.E. & Schaffer, D.V. Genome engineering using adeno-associated virus: basic and clinical research applications. Mol. Ther. 24, 458–464 (2016).

3. Nathwani, A.C. et al. Long-term safety and efficacy of factor IX gene therapy in hemophilia B. N. Engl. J. Med. 371, 1994–2004 (2014).

4. Nault, J.C. et al. Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas. Nat. Genet. 47, 1187–1193 (2015).

5. Russell, D.W. & Grompe, M. Adeno-associated virus finds its disease. Nat. Genet. 47, 1104–1105 (2015).

Cited by 85 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The longitudinal kinetics of AAV5 vector integration profiles and evaluation of clonal expansion in mice;Molecular Therapy - Methods & Clinical Development;2024-09

2. Viral cis-regulatory elements as sensors of cellular states and environmental cues;Trends in Genetics;2024-09

3. Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article;Human Gene Therapy;2024-08-01

4. Preclinical development of a dual targeting bicistronic gene therapy approach for the treatment of wet age-related macular degeneration;2024-07-22

5. rAAV capsid mutants eliminate leaky expression from DNA donor template for homologous recombination;Nucleic Acids Research;2024-05-23