NaCl enhances CD8+ T cell effector functions in cancer immunotherapy
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Published:2024-08-28
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ISSN:1529-2908
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Container-title:Nature Immunology
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language:en
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Short-container-title:Nat Immunol
Author:
Scirgolea Caterina, Sottile RosaORCID, De Luca MarcoORCID, Susana Alberto, Carnevale Silvia, Puccio SimoneORCID, Ferrari Valentina, Lise VeronicaORCID, Contarini Giorgia, Scarpa Alice, Scamardella Eloise, Feno Simona, Camisaschi Chiara, De Simone Gabriele, Basso Gianluca, Giuliano DesireeORCID, Mazza Emilia Maria CristinaORCID, Gattinoni LucaORCID, Roychoudhuri Rahul, Voulaz Emanuele, Di Mitri Diletta, Simonelli Matteo, Losurdo Agnese, Pozzi Davide, Tsui CarlsonORCID, Kallies AxelORCID, Timo Sara, Martano GiuseppeORCID, Barberis Elettra, Manfredi Marcello, Rescigno MariaORCID, Jaillon Sebastien, Lugli EnricoORCID
Funder
Associazione Italiana per la Ricerca sul Cancro Cancer Research Institute
Publisher
Springer Science and Business Media LLC
Reference81 articles.
1. Mahnke, Y. D., Brodie, T. M., Sallusto, F., Roederer, M. & Lugli, E. The who’s who of T-cell differentiation: human memory T-cell subsets. Eur. J. Immunol. 43, 2797–2809 (2013). 2. McLane, L. M., Abdel-Hakeem, M. S. & Wherry, E. J. CD8 T cell exhaustion during chronic viral infection and cancer. Annu. Rev. Immunol. 37, 457–495 (2019). 3. Alfei, F. et al. TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature 571, 265–269 (2019). 4. Joyce, J. A. & Fearon, D. T. T cell exclusion, immune privilege, and the tumor microenvironment. Science 348, 74–80 (2015). 5. Zehn, D., Thimme, R., Lugli, E., de Almeida, G. P. & Oxenius, A. ‘Stem-like’ precursors are the fount to sustain persistent CD8+ T cell responses. Nat. Immunol. 23, 836–847 (2022).
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