Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76-Reference-Cited by-同舟云学术

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Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76

Published:2005-11-06 Issue:12 Volume:6 Page:1253-1262
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Yokosuka Tadashi,Sakata-Sogawa Kumiko,Kobayashi Wakana,Hiroshima Michio,Hashimoto-Tane Akiko,Tokunaga Makio,Dustin Michael L,Saito Takashi

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni1272.pdf

Reference45 articles.

1. Monks, C.R., Freiberg, B.A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82–86 (1998).

2. Grakoui, A. et al. The immunological synapse: a molecular machine controlling T cell activation. Science 285, 221–227 (1999).

3. Huppa, J.B. & Davis, M.M. T-cell-antigen recognition and the immunological synapse. Nat. Rev. Immunol. 3, 973–983 (2003).

4. Dustin, M.L. & Cooper, J.A. The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nat. Immunol. 1, 23–29 (2000).

5. Vicente-Manzanares, M. & Sanchez-Madrid, F. Role of the cytoskeleton during leukocyte responses. Nat. Rev. Immunol. 4, 110–122 (2004).

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