The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE

Author:

Rottman James B.,Smith Tammy,Tonra James R.,Ganley Kenneth,Bloom Troy,Silva Robert,Pierce Barbara,Gutierrez-Ramos Jose-Carlos,Özkaynak Engin,Coyle Anthony J.

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference39 articles.

1. Lenschow, D. J., Walunas, T. L. & Bluestone, J. A. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14, 233–258 (1996).

2. Perrin, P. J. et al. Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis. J. Immunol. 163, 1704–1710 (1999).

3. Tada, Y. et al. CD28-deficient mice are highly resistant to collagen-induced arthritis. J. Immunol. 162, 203–208 (1999).

4. Mathur, M. et al. CD28 interactions with either CD80 or CD86 are sufficient to induce allergic airway inflammation in mice. Am. J. Respir. Cell. Mol. Biol. 21, 498–509 (1999).

5. Kopf, M. et al. Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. J. Exp. Med. 192, 53–61 (2000).

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