Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases

Author:

Pettipher Roy,Hansel Trevor T.,Armer Richard

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Reference134 articles.

1. Urade, Y. & Hayaishi, O. Prostaglandin D2 and sleep regulation. Biochim. Biophys. Acta 1436, 606–615 (1999).

2. Eguchi, N. et al. Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice. Proc. Natl Acad. Sci. USA 96, 726–730 (1999).

3. Lewis, R. A. et al. Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. J. Immunol. 129, 1627–1631 (1982).

4. Peters, S. P. et al. The role of prostaglandin D2 in IgE-mediated reactions in man. Trans. Assoc. Am. Physicians 95, 221–228 (1982).

5. Urade, Y., Ujihara, M., Horiguchi, Y., Ikai, K. & Hayaishi, O. The major source of endogenous prostaglandin D2 production is likely antigen-presenting cells. Localization of glutathione-requiring prostaglandin D synthetase in histiocytes, dendritic, and Kupffer cells in various rat tissues. J. Immunol. 143, 2982–2989 (1989).

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