Distributed 2D temperature sensing during nanoparticles assisted laser ablation by means of high-scattering fiber sensors

Author:

Ashikbayeva Zhannat,Aitkulov Arman,Jelbuldina Madina,Issatayeva Aizhan,Beisenova Aidana,Molardi Carlo,Saccomandi Paola,Blanc Wilfried,Inglezakis Vassilis J.,Tosi Daniele

Abstract

AbstractThe high demand in effective and minimally invasive cancer treatments, namely thermal ablation, leads to the demand for real-time multi-dimensional thermometry to evaluate the treatment effectiveness, which can be also assisted by the use of nanoparticles. We report the results of 20-nm gold and magnetic iron oxide nanoparticles-assisted laser ablation on a porcine liver phantom. The experimental set-up consisting of high-scattering nanoparticle-doped fibers was operated by means of a scattering–level multiplexing arrangement and interrogated via optical backscattered reflectometry, together with a solid-state laser diode operating at 980 nm. The multiplexed 2-dimensional fiber arrangement based on nanoparticle-doped fibers allowed an accurate superficial thermal map detected in real-time.

Funder

SMARTER

EPICGuide

LASEROPTIMAL@POLIMI

Nice-DREAM

NanoSlim

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

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