Burden of unique and low prevalence somatic mutations correlates with cancer survival
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-41015-5.pdf
Reference38 articles.
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2. Birkbak, N. J. et al. Tumor mutation burden forecasts outcome in ovarian cancer with BRCA1 or BRCA2 mutations. PLoS One 8, e80023, https://doi.org/10.1371/journal.pone.0080023 (2013).
3. Rizvi, N. A. et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 348, 124–128, https://doi.org/10.1126/science.aaa1348 (2015).
4. Xiao, D. et al. Analysis of ultra-deep targeted sequencing reveals mutation burden is associated with gender and clinical outcome in lung adenocarcinoma. Oncotarget 7, 22857–22864, https://doi.org/10.18632/oncotarget.8213 (2016).
5. Chalmers, Z. R. et al. Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden. Genome Med 9, 34, https://doi.org/10.1186/s13073-017-0424-2 (2017).
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