Author:
Adams Wilson R.,Mehl Brian,Lieser Eric,Wang Manqing,Patton Shane,Throckmorton Graham A.,Jenkins J. Logan,Ford Jeremy B.,Gautam Rekha,Brooker Jeff,Jansen E. Duco,Mahadevan-Jansen Anita
Abstract
AbstractThe ability to characterize the combined structural, functional, and thermal properties of biophysically dynamic samples is needed to address critical questions related to tissue structure, physiological dynamics, and disease progression. Towards this, we have developed an imaging platform that enables multiple nonlinear imaging modalities to be combined with thermal imaging on a common sample. Here we demonstrate label-free multimodal imaging of live cells, excised tissues, and live rodent brain models. While potential applications of this technology are wide-ranging, we expect it to be especially useful in addressing biomedical research questions aimed at the biomolecular and biophysical properties of tissue and their physiology.
Funder
Air Force Office of Scientific Research
American Society for Engineering Education
Publisher
Springer Science and Business Media LLC
Cited by
10 articles.
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