An engineered arginine-rich α-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice
Author:
Funder
Tzu Chi University
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-32981-3.pdf
Reference74 articles.
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3. Perez, F. et al. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrobial agents and chemotherapy 51, 3471–3484, https://doi.org/10.1128/AAC.01464-06 (2007).
4. Lopez-Perez, P. M., Grimsey, E., Bourne, L., Mikut, R. & Hilpert, K. Screening and Optimizing Antimicrobial Peptides by Using SPOT-Synthesis. Frontiers in chemistry 5, 25, https://doi.org/10.3389/fchem.2017.00025 (2017).
5. Ganz, T. Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol 3, 710–720, https://doi.org/10.1038/nri1180 (2003).
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